mannitol /man″itol/ , a poorly metabolized sugar used as an osmotic diuretic and in kidney function tests. ▪ INDICATIONS: It is prescribed to promote diuresis, decrease intraocular and intracranial pressure, promote the excretion of poisons and other toxic wastes, and evaluate renal function. ▪ CONTRAINDICATIONS: Pulmonary edema, dehydration, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are pulmonary edema, heart failure, hyponatremia, headache, vomiting, and confusion.
