mal de Meleda /mal·də mel′ədä/ [Fr, meleda, sickness] , a chronic autosomal-recessive form of keratoderma of the palms and soles of the feet, in which the hyperkeratosis spreads to involve the dorsal aspects of the hands and feet and other areas of the body, with erythematous, scaling, malodorous cutaneous lesions that may cause deep fissuring. Also called Meleda disease.
