macroglobulinemia /mak′rōglob′yo͝olinē″mē·ə/ [Gk, makros + L, globulus, small ball; Gk, haima, blood] , plasma presence of a high-molecular-weight globulin such as alpha2-macroglobulin or an immunoglobulin of the IgM isotype. Macroglobulins raise plasma viscosity and are associated with monoclonal gammopathies of undetermined significance. Also called Waldenström’s macroglobulinemia. Also spelled macroglobulinaemia. See also multiple myeloma.
