macrocyte /mak′rəsīt/ [Gk, makros + kytos, cell] , an erythrocyte that exceeds 9 μm in diameter on a peripheral blood film, associated with an MCV greater than 100 fL. Macrocytes are seen in liver disease, alcoholism, megaloblastic anemia with folate or cobalamin deficiency, and in myelodysplastic syndromes. Compare microcyte. See also macrocytic anemia.