lubiprostone, a miscellaneous GI agent. ▪ INDICATIONS: This drug is used to treat chronic idiopathic constipation. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug and GI obstruction prohibit its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include dizziness, depression, fatigue, insomnia, hypertension, chest pain, abdominal distension, constipation, diarrhea, dry mouth, dyspepsia, flatulence, gastroenteritis, viral gastroesophageal reflux disease, vomiting, fecal incontinence, fecal urgency, urinary tract infection, chest pain, peripheral edema, influenza, pyrexia, viral infection, back pain, arthralgia, muscle cramps, pain in extremities, bronchitis, cough, dyspnea, nasopharyngitis, sinusitis, and upper respiratory infection. Common side effects include headache, nausea, abdominal pain, and eructation.
