Lown-Ganong-Levine (LGL) syndrome /loun″ gənong″ ləvēn″/ [Bernard Lown, American physician, b. 1921; William F. Ganong, American physiologist, b. 1924; S.A. Levine, American physician, 1891–1966] , a disorder of the atrioventricular (AV) conduction system marked by ventricular preexcitation. Part or all of the AV nodal connection is bypassed by an abnormal connection between the atria and the bundle of His. The condition may be discovered by routine electrocardiogram or may be seen in association with paroxysmal atrial arrhythmias, supraventricular tachycardia, atrial flutter, and fibrillation. Treatments include the use of antiarrhythmic drugs such as quinidine sulfate, procainamide, and propranolol; surgical interruption of the abnormal pathway; and implantation of a pacemaker. Also called short-PR-normal-QRS syndrome. Compare Wolff-Parkinson-White syndrome.
