lithium carbonate, an antimanic agent. ▪ INDICATIONS: It is prescribed in the treatment of manic episodes of manic-depressive disorder. ▪ CONTRAINDICATIONS: It is used with caution in the presence of renal or cardiovascular disease and is not recommended for children under 12 years of age. Pregnancy or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are renal damage, polydipsia and polyuria, and impairment of mental and physical abilities. Retention of sodium and fluid may occur.