Libman-Sacks endocarditis /lib″mən saks″/ [Emanuel Libman, American physician, 1872–1946; Benjamin Sacks, American physician, 1896–1939] , the most common manifestation of lupus erythematosus, characterized by warty lesions that develop near the heart valves but rarely affect valvular action. The lesions usually are dry and granular, with a pink or tawny color. They contain basophilic cellular debris and develop in the angle of the atrioventricular valves and at the base of the mitral valve. Also called Libman-Sacks disease, Libman-Sacks syndrome.