juxtaglomerular cells [L, juxta, near, glomerulus, small ball, cella, storeroom] , smooth myoepithelioid cells lining the glomerular end of the afferent arterioles in the kidney that are in opposition to the macula densa region of the early distal tubule. These cells synthesize and store renin and release it in response to decreased renal perfusion pressure, increased sympathetic nerve stimulation of the kidneys, or decreased sodium concentration in fluid in the distal tubule.