Jod-Basedow phenomenon /jod′ bä″zədō′/ [Ger, Jod, iodine; Karl A. von Basedow, German physician, 1799–1854] , thyrotoxicosis that may occur when dietary iodine is given to a patient with endemic goiter in an area of environmental iodine deficiency. It is presumed that iodine deficiency protects some patients with endemic goiter from development of thyrotoxicosis. The phenomenon may also occur when large doses of iodine are given to patients with nontoxic multinodular goiter in areas with sufficient environmental iodine. Also called iodine-induced hyperthyroidism.