infantile myofibromatosis, a condition present at birth or occurring soon after, characterized by one or more firm, rubbery, spherical or ovoid nodules in the skin and subcutaneous tissue. The nodules are composed of myofibroblasts and may undergo ulceration and calcification. In about half of patients, skeletal fibromas also occur. When lesions are limited to the skin and bones (a condition sometimes known as congenital multiple fibromatosis), prognosis is good and lesions resolve spontaneously. Visceral involvement may also occur (congenital generalized fibromatosis) and is highly lethal.