imbalance /imbal″əns/ [L, im, not, bilanx, having two scales] , 1. a lack of balance between opposing muscle groups, such as in the imbalance of extraocular muscles leading to strabismus. 2. an abnormal balance of fluid and electrolytes in the body tissues. 3. the unequal distribution of subjects in a population group, such as the only girl in a large family of boys. 4. a lack of balance in a person with mental abilities that are remarkable in one area but deficient in others, as in an idiot savant.