hypertrophic cardiomyopathy, an abnormal condition characterized by gross hypertrophy of the interventricular septum and left ventricular free wall of the heart. Ventricular hypertrophy results in impaired diastolic filling and reduced cardiac output. Signs and symptoms, such as fatigue and syncope, are often associated with exercise when the demand for increased cardiac output cannot be met. This is commonly a genetic disease, with numerous genes implicated. Also called hypertrophic obstructive cardiomyopathy.
