hydrocortisone /-kôr″tisōn/ , a topical corticosteroid. ▪ INDICATIONS: It is prescribed for the topical treatment of skin inflammation. ▪ CONTRAINDICATIONS: Viral and fungal diseases of the skin that occur where circulation is impaired or known hypersensitivity to steroids prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are various systemic side effects that may result from prolonged or excessive use. Local irritation of the skin may occur.