hydrocodone bitartrate /-kō″dōn/ , an opioid antitussive and analgesic. ▪ INDICATIONS: It is prescribed in the treatment of cough and moderate to severe pain. ▪ CONTRAINDICATIONS: Drug dependence or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are drug dependence and respiratory and circulatory depression.