hormone replacement therapy, the administration of sex hormones following menopause or hysterectomy or in amenorrhea. There are a number of indications, including the induction of menses in amenorrhea. If used for postmenopausal symptoms, it should be given in the smallest effective dose for the shortest period of time. Following the completion of the Women’s Health Initiative study, hormone replacement therapy is no longer used for the prevention of osteoporosis or coronary artery disease.
