Hers’ disease /herz, hurz/ [H.G. Hers, 20th-century Belgian physiologist; L, dis, opposite of; Fr, aise, ease] , an uncommon metabolic disorder of glycogen storage involving a deficiency of glycogen phosphorylase. It is characterized by hepatomegaly and an accumulation of abnormally large amounts of glycogen in the liver as a result of its inability to break down glycogen. The condition is inherited as an autosomal-recessive trait. There is no known treatment. Also called glycogen storage disease, type VI. See also glycogen storage disease.