glomerulosclerosis

glomerulosclerosis /-sklərō″sis/ [L, glomerulus, small ball; Gk, sklerosis, a hardening, osis, condition] , a severe kidney disease in which glomerular function of blood filtration is lost as fibrous scar tissue replaces the glomeruli. The disease commonly follows an infection or arteriosclerosis.

Glomerulosclerosis (Courtesy Dr. H. Rennke, Department of Pathology, Brigham and Women’s Hospital)