globus hystericus /glō″bus/ [L, small ball; Gk, hystera, womb] , a transitory sensation of a lump in the throat that cannot be swallowed or coughed up, often accompanying emotional conflict or acute anxiety. The condition is thought to be caused by a functional disturbance of the ninth cranial nerve and spasm of the inferior constrictor muscle that encircles the lower part of the throat. The physical examination result tends to be normal, as does the result of barium esophagography.