Gianotti-Crosti syndrome /jänot′ē kros′tē/ [Fernando Gianotti, Italian dermatologist, 1920–1984; Agostino Crosti, 20th-century Italian dermatologist] , a generally benign and self-limited disease of young children that had previously been associated with hepatitis B virus but is now known to occur in other viral illnesses. It is characterized by the appearance of crops of usually nonpruritic, dusky or coppery red, flat-topped, firm papules forming a symmetric eruption on the face, buttocks, and limbs, including the palms and soles, and associated with malaise, low-grade fever, and a few other symptoms. Also called acrodermatitis papulosa infantum, infantile acrodermatitis, papular acrodermatitis of childhood.
