gatifloxacin, a broad-spectrum antiinfective. ▪ INDICATIONS: It is used to treat acute bacterial exacerbation of chronic bronchitis, acute sinusitis, community-acquired pneumonia, gonorrhea, and infections caused by susceptible Escherichia coli, Staphylococcus aureus, Haemophilus influenzae, H. parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Neisseria gonorrhoeae, Proteus mirabilis, Chlamydia pneumoniae, Legionella pneumophila, and Mycoplasma pneumoniae. ▪ CONTRAINDICATIONS: Known hypersensitivity to quinolones prohibits its use. ▪ ADVERSE EFFECTS: Pseudomembranous colitis is a life-threatening effect. Other adverse effects include dizziness, insomnia, paresthesia, tremor, vasodilation, increased aspartate aminotransferase and alanine aminotransferase, pruritus, urticaria, photosensitivity, flushing, fever, and chills. Common side effects include headache, nausea, diarrhea, rash, dyspnea, and pharyngitis.
