ganirelix, a gonadotropin-releasing hormone antagonist. ▪ INDICATIONS: It is used to inhibit premature luteinizing hormone surges in women undergoing controlled ovarian hyperstimulation. ▪ CONTRAINDICATIONS: Pregnancy, lactation, latex allergy, and known hypersensitivity to this drug prohibit its use. ▪ ADVERSE EFFECTS: Fetal death is a life-threatening consequence of this drug’s use. Other adverse effects include headache, ovarian hyperstimulation syndrome, gynecological abdominal pain, nausea, and pain on injection. Common side effects include spotting and breakthrough bleeding.