frozen section method [AS, freosan, to freeze; L, sectio, a cutting; Gk, meta, order, hodos, path] , (in surgical pathology) a method used in preparing a selected portion of tissue for pathological examination. The tissue is moistened and, fixed or unfixed, is rapidly frozen and cut by a microtome in a cryostat. This method is very rapid, allowing the pathologist to examine the specimen during a surgical procedure.