flutamide, a hormonal (antiandrogen) antineoplastic agent. ▪ INDICATIONS: It is prescribed along with leuprolide in the treatment of metastatic prostate cancer and other cancers stimulated by male hormones and is sometimes used to treat female hirsutism. ▪ CONTRAINDICATIONS: It should not be given to patients who are allergic to the product. Hormonal medications should be avoided or used with extreme caution by women who are breastfeeding or who may be pregnant. Anticoagulants may interact with flutamide. ▪ ADVERSE EFFECTS: The side effects most often reported include hot flashes, loss of sex drive, impotence, nausea, vomiting, breast enlargement, and stomach upset.