factor IX complex, a hemostatic containing factors II, VII, IX, and X. ▪ INDICATIONS: It is prescribed in the treatment of hemophilia B. It is a vitamin K–dependent protein synthesized in the liver. ▪ CONTRAINDICATIONS: Liver disease with associated intravascular coagulation and fibrinolysis is the only contraindication. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are hepatitis, intravascular coagulation, circulatory collapse, and hypersensitivity reaction.
