ethacrynic acid /eth′əkrin″ik/ , a loop diuretic. ▪ INDICATIONS: It is prescribed as a treatment for severe edema, such as nephrotic syndrome, hepatic cirrhoses, and ascites of malignancy. Unlike many other diuretics, ethacrynic acid is not a sulfonamide derivative and can therefore be tolerated by some people who develop hypersensitivity reactions to other diuretics. ▪ CONTRAINDICATIONS: Pregnancy, anuria, or known hypersensitivity to this drug prohibits its use. It is not given to infants. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are tetany, muscle weakness, cramps, and excessive diuresis. Hearing loss may occur.
