etanercept, a biological agent. ▪ INDICATIONS: It is used to treat acute or chronic rheumatoid arthritis that has not responded to other treatments. ▪ CONTRAINDICATIONS: Known hypersensitivity and sepsis prohibit its use. ▪ ADVERSE EFFECTS: Adverse effects include abdominal pain, dyspepsia, headache, asthenia, dizziness, injection site reaction, cough, upper respiratory infection, non-upper respiratory infection, and sinusitis. Common side effects include rash, pharyngitis, and rhinitis.