erythromycin /erith′rōmī″sin/ , an antibiotic (of the macrolide type). ▪ INDICATIONS: It is prescribed in the treatment of many bacterial and mycoplasmic infections, particularly those that cannot be treated by penicillin. ▪ CONTRAINDICATIONS: Liver disease or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: The more serious adverse effects result from its effects on the metabolism of other drugs, which have led to fatalities. Cholestatic hepatitis, hypersensitivity reactions, and GI discomfort are other adverse effects associated with its use.