enfuvirtide, an antiretroviral drug. ▪ INDICATIONS: This drug is used in combination with other antiretrovirals to treat HIV-1 infection. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include anxiety, peripheral neuropathy, taste disturbance, insomnia, depression, abdominal pain, anorexia, constipation, pancreatitis, injection site reactions, influenza, cough, conjunctivitis, lymphadenopathy, myalgia, hyperglycemia, and pneumonia. Life-threatening side effects include glomerulonephritis, renal failure, Guillain-Barré syndrome, thrombocytopenia, and neutropenia.
