dysfunctional uterine bleeding (DUB), abnormal uterine bleeding that is not caused by a tumor, inflammation, or pregnancy. It may be characterized by painless, irregular heavy bleeding or intermenstrual spotting or periods of amenorrhea. The condition is associated with anovulation and unopposed estrogen stimulation. The plan of treatment depends on the patient’s age and may include dilation and curettage and use of hormones and other medications.