Duane’s syndrome

Duane’s syndrome /dwānz/ [Alexander Duane, American ophthalmologist, 1858–1926] , an autosomal-dominant syndrome in which the affected eye shows limitation or absence of abduction, restriction of adduction, retraction of the globe on adduction, narrowing of the palpebral fissure on adduction and widening on abduction, and deficient convergence. It can be either unilateral or bilateral. It is caused by abnormal innervation of the third and sixth cranial nerves.