doxycycline /dok′sisī″klēn/ , a tetracycline antibiotic. ▪ INDICATIONS: It is prescribed in the treatment of infections caused by susceptible bacterial strains, especially Chlamydia, Rickettsia, and Mycoplasma . ▪ CONTRAINDICATIONS: Renal or liver dysfunction or known hypersensitivity to this drug or to other tetracycline medication prohibits its use. It is not given during pregnancy or to children less than 8 years of age. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are GI disturbances, phototoxicity, potentially serious superinfections, and hypersensitivity reactions. Discoloration of teeth may occur in children exposed to the drug in utero or under 8 years of age.