dimercaprol /dī′mərkap″rol/ , a heavy-metal antagonist. Formerly called British antilewisite (BAL). ▪ INDICATIONS: It is prescribed in the treatment of Wilson’s disease and in the treatment of acute arsenic, mercury, or gold poisoning, as from an overdosage with mercurial diuretics, arsenics, or gold salts. ▪ CONTRAINDICATIONS: Hepatic or renal insufficiency; poisoning with cadmium, iron, or selenium; or known hypersensitivity to the drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are nephrotoxicity, acidosis, convulsions, and abnormal cardiovascular functions. Mild reactions include pain at the injection site, nausea, excessive salivation, and paresthesia.
