desirudin, an anticoagulant. ▪ INDICATIONS: This drug is used in prophylaxis for deep vein thrombosis in those undergoing hip replacement. ▪ CONTRAINDICATIONS: Known hypersensitivity to natural or synthetic hirudins, active bleeding, and irreversible coagulation disorders prohibit this drug’s use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include injection site mass, nausea, deep thrombophlebitis, anemia, and hypersensitivity. Life-threatening side effects include bleeding and hemorrhage.
