desipramine hydrochloride /desip″rəmēn/ , a tricyclic antidepressant. ▪ INDICATIONS: It is prescribed in the treatment of mental depression and as adjunctive therapy for the treatment of chronic pain. ▪ CONTRAINDICATIONS: Concomitant administration of monoamine oxidase inhibitors, heart block, recent myocardial infarction, or known hypersensitivity to this drug or to tricyclic medication prohibits its use. It is used with caution in patients who have seizure disorders or cardiovascular disease. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are sedation as well as GI, cardiovascular, and neurological reactions. This drug interacts with many other drugs.
