deferoxamine mesylate /dē′fərok″səmēn/ , a chelating agent with specific affinity for ferric iron and low affinity for calcium. ▪ INDICATIONS: It is prescribed in the treatment of acute iron intoxication and chronic iron overload. ▪ CONTRAINDICATIONS: Renal disease or anuria prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are hypotension, tachycardia, dysuria, visual difficulties, and anaphylactoid reactions.