Crigler-Najjar syndrome /krig″lər naj″är/ [John F. Crigler, Jr., American pediatrician, 1919-; Victor A. Najjar, Lebanese-born American microbiologist, 1914-2002] , a congenital familial autosomal anomaly, in which glucuronyl transferase, an enzyme, is deficient or absent. The condition is characterized by nonhemolytic jaundice, an accumulation of unconjugated bilirubin in the blood, and severe disorders of the central nervous system. See also hyperbilirubinemia of the newborn.
