creatine /krē″ətēn, -tin/ [Gk, kreas, flesh] , an important nitrogenous compound produced by metabolic processes in the body. Combined with phosphorus, it forms a high-energy phosphate. In normal metabolic reactions the phosphorus is transferred to a molecule of adenosine diphosphate to produce a molecule of very high-energy adenosine triphosphate. See also creatinine.