craniometaphyseal dysplasia /-met′əfiz″ē·əl/ , an inherited bone disorder characterized by paranasal overgrowth, thickening of the skull and jaw, and entrapment of cranial nerves. The long bones have widened, club-shaped metaphyses. The patient may experience nasorespiratory infections, associated with bone overgrowth at the sinuses, and malocclusion of the jaws.