cortisone /kôr″təsōn/ , a synthetic glucocorticoid. ▪ INDICATIONS: It is prescribed for adrenocortical insufficiency inflammation. ▪ CONTRAINDICATIONS: Fungal infections or known hypersensitivity to this drug prohibits its systemic use. Viral or fungal infections of the skin, impaired circulation, or known hypersensitivity to this drug prohibits its topical use. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions to the systemic administration of the drug are GI, endocrine, neurological, fluid, and electrolyte disturbances, so the drug must be used with caution when there are preexisting conditions. Skin reactions may result from topical administration. Therapy lasting longer than a few days can lead to hypothalamic-pituitary-adrenal suppression.
