colistin sulfate /kōlis″tin/ , an antibacterial and steroid agent. ▪ INDICATIONS: It is prescribed topically in the treatment of infections of the outer ear and systemically for the treatment of serious gram-negative infections and gastroenteritis caused by Escherichia coli. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious systemic reactions are respiratory arrest, renal toxicity, and neuromuscular blockade.
