clomiPHENE stimulation test, a test used to evaluate gonadal function in males who show signs of abnormal pubertal development. Clomiphene, a nonsteroidal analog of estrogen, stimulates the hypothalamic-pituitary system to raise follicle-stimulating hormone and luteinizing hormone levels of the blood. Failure to respond to clomiphene indicates hypothalamic-pituitary disease, possibly a pituitary tumor. See also clomiPHENE citrate, gonadotropin.
