clomiPHENE citrate /klō″məfēn/ , a nonsteroidal drug that acts to stimulate ovulation by interacting with estrogen receptors in the hypothalamus in a manner that leads to the release of pituitary gonadotropins. ▪ INDICATIONS: It is prescribed primarily for the treatment of anovulation and oligoovulation in women desiring pregnancy. ▪ CONTRAINDICATIONS: Abnormal vaginal bleeding, liver dysfunction, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are enlargement of the ovaries, hot flashes, blurred vision, gastric upset, rashes, and abdominal pain.
