cilostazol, a platelet aggregation inhibitor. ▪ INDICATIONS: It is used to treat intermittent claudication. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug, congestive heart failure, active liver disease, blood dyscrasias, and active bleeding prohibits its use. ▪ ADVERSE EFFECTS: Life-threatening effects include atrial fibrillation/flutter, cerebral infarct, cerebral ischemia, congestive heart failure, cardiac arrest, myocardial infarction, nodal dysrhythmias, bleeding (epistaxis, hematuria, conjunctival hemorrhage, GI bleeding), agranulocytosis, neutropenia, and thrombocytopenia. Serious adverse effects include palpitations, tachycardia, vomiting, colitis, cholelithiasis, ulcer, and diabetes mellitus. Common side effects include vertigo, diarrhea, rash, back pain, headache, infection, myalgia, peripheral edema, cough, pharyngitis, and rhinitis.
