cidofovir, an antiviral. ▪ INDICATIONS: It is used to treat cytomegalovirus retinitis in patients with AIDS. ▪ CONTRAINDICATIONS: Known hypersensitivity to acyclovir or this drug prohibits its use. ▪ ADVERSE EFFECTS: Life-threatening effects include coma, hemorrhage, hematuria, granulocytopenia, thrombocytopenia, irreversible neutropenia, anemia, and eosinophilia. Other serious adverse effects include confusion, psychosis, tremors, somnolence, arrhythmias, hypertension/hypotension, retinal detachment in cytomegalovirus retinitis, abnormal liver function tests, increased creatinine, increased blood urea nitrogen, and phlebitis.