chronic myelogenous leukemia /mī′əlōsit″ik/ , myeloproliferative neoplasm characterized by the unregulated and excessive production of cells of the myelocytic maturation series and presence of the BCR/ABL 1 mutation. Also called chronic myelocytic leukemia. Compare acute lymphocytic leukemia, chronic lymphocytic leukemia, leukemoid reaction. See also acute myeloid leukemia, leukocytosis.