chlortetracycline hydrochloride /-tet′rəsī″klēn/ , a tetracycline antibiotic used as a topical antiinfective. ▪ INDICATIONS: It is prescribed in the treatment of bacterial infections. ▪ CONTRAINDICATIONS: It is available topically only and has little systemic effect. Known hypersensitivity to this drug or to other tetracycline medication prohibits its use. ▪ ADVERSE EFFECTS: Burning, stinging, and yellowing of the skin may occur.