chlorproPAMIDE /-prō″pəmīd/ , an oral antidiabetic of the sulfonylurea class. ▪ INDICATIONS: It is prescribed in the treatment of non–insulin-dependent diabetes mellitus. ▪ CONTRAINDICATIONS: Liver or kidney dysfunction or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse reactions are hematologic derangements and jaundice. Hypoglycemia, GI distress, and rashes are common adverse effects.