chlorproMAZINE /-prō″məzēn/ , a phenothiazine drug used as an antipsychotic and antiemetic. ▪ INDICATIONS: It is prescribed in the treatment of psychotic disorders (mania, schizophrenia), severe nausea and vomiting, and intractable hiccups. ▪ CONTRAINDICATIONS: Parkinson’s disease, concurrent administration of central nervous system depressants, liver or renal dysfunction, severe hypotension, or known hypersensitivity to this drug or to other phenothiazine medication prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are hypotension, alteration in cardiac conduction, liver toxicity, a variety of extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.
