Chagres fever /chag″ris/ [Chagres River, Panama; L, febris] , a phlebotomus arbovirus infection transmitted to humans through the bite of a sandfly. The disease is rarely fatal and is characterized by fever, headache, and muscle pains of the chest or abdomen. There may be nausea and vomiting, giddiness, weakness, photophobia, and pain on moving the eyes. The infection usually subsides within a week. Supportive treatment includes analgesics, bed rest, and adequate fluid intake. The disease is most common in Central America. Also called Panama fever.